Lymphatic drug delivery system (LDDS) is an effective therapy for the treatment of metastatic lymph nodes.

The anticancer drug is administered directly to the metastatic lymph nodes.

We found that optimization of solvent properties of anticancer drugs enhanced their antitumor effects. [1]

Cover of this issue. Intranodal lymphangiography of the proper axillary lymph node using a contrast-enhanced high-frequency ultrasound imaging system. See also Fukumura et al. (pp. 1735–1745 of this issue).

Reference

[1] R. Fukumura, A. Sukhbaatar, R. Mishra, M. Sakamoto, S. Mori, T. Kodama, Study of the physicochemical properties of drugs suitable for administration using a lymphatic drug delivery system, Cancer Science, 112 (2021) 1735-1745.