We developed a method by injecting drugs into the sentinel lymph node (SLN) to treat the SLN and its downstream metastatic lymph nodes (LNs).

The flow of the fluorescent dye from the upstream to the downstream LN simulates anticancer drugs’ flow. [1, 2]

References
[1] T. Kodama, Y. Hatakeyama, S. Kato, S. Mori, Visualization of fluid drainage pathways in lymphatic vessels and lymph nodes using a mouse model to test a lymphatic drug delivery system, Biomedical Optics Express, 6 (2015) 124-134.
[2] Youtube, Visualization of fluid drainage pathways in lymphatic vessels and lymph nodes using a mouse model to test a lymphatic drug delivery system: https://www.youtube.com/watch?v=SHXb2EI5b_s, in: YouTube (Ed.), 2015.