Infrared spectra of 2-hydroxypyridine (2HP) and its hydrogen-bonded clusters with water and methanol have been observed by IR-UV double-resonance spectroscopy. The OH stretching vibrations of the 2HP site as well as either the water or methanol site were observed. The spectra were compared with those of the corresponding clusters of 2-pyridone (2PY), which have been reported in J. Chem. Phys. 1999, 110, 8397. The OH stretching vibration of bare 2HP was observed at 3600 cm^-1, representing a clear difference from the NH stretching vibration of 2PY (3441 cm^-1). On the other hand, the IR spectra of the 2HP-water and -methanol clusters were found to be very similar to those of the corresponding clusters of 2PY, indicating a sovation-mediated tautomerization between 2HP and 2PY. The cluster structures were examined using ab initio molecular orbital calculation.